KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D22B
All Species:
11.21
Human Site:
T118
Identified Species:
22.42
UniProt:
Q9NU19
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NU19
NP_060242.2
505
59081
T118
P
E
R
S
Q
S
T
T
S
D
V
P
A
N
Y
Chimpanzee
Pan troglodytes
XP_527375
505
59106
T118
P
E
R
S
Q
S
T
T
S
D
V
P
A
N
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538894
488
57073
L119
K
S
S
S
D
A
Q
L
S
E
N
S
S
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5A6
516
59344
P129
E
P
Q
P
I
A
E
P
P
V
P
P
S
G
D
Rat
Rattus norvegicus
NP_001020230
505
59036
T118
P
E
R
S
Q
S
T
T
S
D
V
P
A
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509397
560
64265
V120
D
V
P
G
N
C
K
V
I
K
S
S
S
D
A
Chicken
Gallus gallus
XP_419261
747
85990
L360
P
E
R
V
Q
P
T
L
S
D
M
P
T
N
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685523
523
60664
E136
I
S
T
N
P
D
Q
E
R
L
D
V
E
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650941
546
61493
Q154
E
T
H
S
R
S
N
Q
N
H
N
A
S
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023165
495
56525
S118
E
P
L
P
S
S
V
S
S
T
P
Q
T
A
N
Sea Urchin
Strong. purpuratus
XP_797601
498
57012
D120
V
S
E
R
T
E
S
D
V
R
I
P
N
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08484
637
73271
T188
T
P
V
A
P
T
R
T
L
S
R
K
S
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
95.4
N.A.
62.2
98.4
N.A.
79.6
63.3
N.A.
70.1
N.A.
43
N.A.
46.9
46.7
Protein Similarity:
100
100
N.A.
96
N.A.
76.7
99
N.A.
83.5
65.1
N.A.
81.6
N.A.
57.6
N.A.
62.1
65.5
P-Site Identity:
100
100
N.A.
13.3
N.A.
6.6
100
N.A.
0
60
N.A.
0
N.A.
13.3
N.A.
13.3
6.6
P-Site Similarity:
100
100
N.A.
40
N.A.
26.6
100
N.A.
13.3
66.6
N.A.
13.3
N.A.
33.3
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
17
0
0
0
0
0
9
25
9
17
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
0
0
0
9
9
0
9
0
34
9
0
0
17
9
% D
% Glu:
25
34
9
0
0
9
9
9
0
9
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
9
0
9
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
9
0
0
9
0
9
0
0
0
% K
% Leu:
0
0
9
0
0
0
0
17
9
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
9
0
9
0
9
0
17
0
9
34
9
% N
% Pro:
34
25
9
17
17
9
0
9
9
0
17
50
0
9
0
% P
% Gln:
0
0
9
0
34
0
17
9
0
0
0
9
0
0
0
% Q
% Arg:
0
0
34
9
9
0
9
0
9
9
9
0
0
9
0
% R
% Ser:
0
25
9
42
9
42
9
9
50
9
9
17
42
9
17
% S
% Thr:
9
9
9
0
9
9
34
34
0
9
0
0
17
9
9
% T
% Val:
9
9
9
9
0
0
9
9
9
9
25
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _